Kapcsolat
Hogyan vásároljunk
Kézbesítés
Vásárlási tanácsadó
Novel Therapeutic Agents for the Treatment of Prostate Cancer
Angol
189 b
30 nap a termék visszaküldésére
Ezt is ajánljuk
Standard hormonal therapy with currently available §anti-androgens and LHRH analogs becomes ineffective §in the hormone-refractory stage of prostate cancer §due to the changes in androgen receptor signaling §axis in prostate cancer cells. To develop effective §therapies against hormone-refractory prostate §cancer, §novel agents targeting multiple points at the §cellular signaling cascades are needed in order to §produce the maximal therapeutic efficacy against §late §stage prostate cancer. In this dissertation work, we §have presented the design and development of novel §agents targeting three key signaling pathways §towards §their ultimate development into the effective §therapies against hormone refractory prostate §cancer. §Specifically, we have discovered and designed a §diverse array of novel molecules targeting the AR §signaling pathway, the sarco-endoplasmic reticulum §calcium ATPase pump driven calcium homeostasis and §the proteolytic activity of prostate specific §antigen §.
Információ a könyvről
Angol
