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This second volume of the new series on vaccinology is devoted broadly to vaccines against communicable diseases. Key issues discuss the practicability and efficacy of universal vaccination and the benefits for public health especially in developing countries. Chapters concerning problems with storage of supplies of vaccines in active form, and new technologies applied to the manufacturing of vaccines are included. Epidemiological studies and prospects as well as various immunological parameters concerning the diagnosis, course and prevention of various viral, bacterial and parasitological diseases such as hepatology, cholera, helminthic infections, lepra and others are comprehensively treated by experts in their respective fields. New approaches in vaccinology such as the use of Vaccinia Virus as vector or the use of liposomes as carrier of vaccines are discussed.